C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: interferon regulatory factor 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000533182 IRF7-007 ENSG00000185507 9606 - 11:612561-615950 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainColonHeartLungPlacentaENST00000533182
Transcript ID Adrenal Brain Colon Heart Lung Placenta
ENST00000533182 3.886±0.00 0.534±0.00 1.836±0.00 0.076±0.00 8.365±0.00 2.410±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006RQ CIL_0006RQ_0002 CGP 11:576486-615999
CIL_0003OO CIL_0003OO_0001 CGP 11:612553-626078

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 TAS negative regulation of transcription from RNA polymerase II promoter
GO:0000975 IEA regulatory region DNA binding
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000982 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0002819 IDA regulation of adaptive immune response
GO:0003677 IMP DNA binding
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 TAS cytoplasm
GO:0005829 TAS cytosol
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006974 TAS cellular response to DNA damage stimulus
GO:0009615 TAS response to virus
GO:0010008 TAS endosome membrane
GO:0019043 TAS establishment of viral latency
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0032479 TAS regulation of type I interferon production
GO:0032481 TAS positive regulation of type I interferon production
GO:0032607 ISS interferon-alpha production
GO:0032608 ISS interferon-beta production
GO:0032727 IDA positive regulation of interferon-alpha production
GO:0032728 TAS positive regulation of interferon-beta production
GO:0034124 ISS regulation of MyD88-dependent toll-like receptor signaling pathway
GO:0034127 ISS regulation of MyD88-independent toll-like receptor signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0039530 TAS MDA-5 signaling pathway
GO:0045087 TAS innate immune response
GO:0045655 TAS regulation of monocyte differentiation
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0050776 TAS regulation of immune response
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:2000110 TAS negative regulation of macrophage apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000155744 Irf7-004 retained_intron Mus_musculus 0 435
ENSMUST00000097952 Irf7-002 protein_coding Mus_musculus 0 435
ENSMUST00000026571 Irf7-001 protein_coding Mus_musculus 0 435
ENSMUST00000106023 Irf7-003 protein_coding Mus_musculus 0 435
ENSMUST00000123525 Irf7-011 protein_coding Mus_musculus 0 333

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