C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ATPase, Na+/K+ transporting, alpha 1 polypeptide
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000537345 ATP1A1-202 ENSG00000163399 9606 + 1:116373867-116404772 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00012S CIL_00012S_0002 CGP 1:116111755-116410261

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0002026 IEA regulation of the force of heart contraction
GO:0002028 ISS regulation of sodium ion transport
GO:0005391 ISS:IEA sodium:potassium-exchanging ATPase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005768 IEA endosome
GO:0005783 ISS endoplasmic reticulum
GO:0005794 ISS Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0005890 IDA sodium:potassium-exchanging ATPase complex
GO:0005901 IEA caveola
GO:0006754 IEA ATP biosynthetic process
GO:0006813 IEA potassium ion transport
GO:0006814 IEA sodium ion transport
GO:0006883 IDA cellular sodium ion homeostasis
GO:0008217 IEA regulation of blood pressure
GO:0010107 IDA potassium ion import
GO:0016020 TAS membrane
GO:0016021 ISS:IEA integral component of membrane
GO:0016311 IEA dephosphorylation
GO:0016323 IEA basolateral plasma membrane
GO:0016324 IEA apical plasma membrane
GO:0016791 IEA phosphatase activity
GO:0019901 IEA protein kinase binding
GO:0019904 IEA protein domain specific binding
GO:0030007 IDA cellular potassium ion homeostasis
GO:0030315 IEA T-tubule
GO:0030506 IEA ankyrin binding
GO:0030955 IEA potassium ion binding
GO:0031402 IEA sodium ion binding
GO:0031947 IEA negative regulation of glucocorticoid biosynthetic process
GO:0031982 IDA vesicle
GO:0034220 TAS ion transmembrane transport
GO:0036376 IDA sodium ion export from cell
GO:0042383 ISS sarcolemma
GO:0042493 IEA response to drug
GO:0043234 IDA protein complex
GO:0043531 IEA ADP binding
GO:0043548 IEA phosphatidylinositol 3-kinase binding
GO:0045121 IEA membrane raft
GO:0045822 IEA negative regulation of heart contraction
GO:0045823 IEA positive regulation of heart contraction
GO:0045989 IEA positive regulation of striated muscle contraction
GO:0046872 IEA metal ion binding
GO:0051087 IPI chaperone binding
GO:0055085 TAS transmembrane transport
GO:0055119 TAS relaxation of cardiac muscle
GO:0060048 TAS cardiac muscle contraction
GO:0060081 IEA membrane hyperpolarization
GO:0070062 IDA extracellular vesicular exosome
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071383 IDA cellular response to steroid hormone stimulus
GO:0086004 IEA regulation of cardiac muscle cell contraction
GO:0086009 IDA membrane repolarization
GO:0086013 IC membrane repolarization during cardiac muscle cell action potential
GO:0086064 TAS cell communication by electrical coupling involved in cardiac conduction
GO:1903416 IDA response to glycoside
GO:1990239 IDA steroid hormone binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000036493 Atp1a1-001 protein_coding Mus_musculus 0 4178
ENSMUST00000080882 Atp1a3-001 protein_coding Mus_musculus 0 1958
ENSMUST00000102858 Atp1a3-002 protein_coding Mus_musculus 0 1940
ENSDART00000006449 atp1a1a.2-001 protein_coding Danio_rerio 0 1240
ENSMUST00000136340 Atp1a1-002 retained_intron Mus_musculus 0 424
ENSMUST00000130649 Atp1a1-003 retained_intron Mus_musculus 0 359

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