C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutamate receptor, metabotropic 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000538487 GRM4-001 ENSG00000124493 9606 - 6:34021851-34146080 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainPlacentaTestisENST00000538487
Transcript ID Brain Placenta Testis
ENST00000538487 0.403±0.32 0.180±0.00 0.288±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000251 CIL_000251_0001 CGP 6:34018645-34246231

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 IDA activation of MAPK activity
GO:0001642 IBA group III metabotropic glutamate receptor activity
GO:0004930 IMP:IEA G-protein coupled receptor activity
GO:0005516 IEA calmodulin binding
GO:0005622 IDA intracellular
GO:0005886 TAS plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007196 IMP adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007269 TAS neurotransmitter secretion
GO:0007612 IEA learning
GO:0008066 IMP glutamate receptor activity
GO:0016021 IEA integral component of membrane
GO:0031410 IDA cytoplasmic vesicle
GO:0042734 IBA presynaptic membrane
GO:0043195 IEA terminal bouton
GO:0043198 IEA dendritic shaft
GO:0043410 IEP positive regulation of MAPK cascade
GO:0043523 TAS regulation of neuron apoptotic process
GO:0048306 IEA calcium-dependent protein binding
GO:0048787 IEA presynaptic active zone membrane
GO:0051966 IBA regulation of synaptic transmission, glutamatergic

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000118161 Grm4-002 protein_coding Mus_musculus 0 3755
ENSMUST00000118489 Grm4-001 protein_coding Mus_musculus 0 3216
ENSDART00000058736 grm4-201 protein_coding Danio_rerio 0 1328
ENSMUST00000171427 Grm6-201 protein_coding Mus_musculus 0 979
ENSMUST00000000631 Grm6-001 protein_coding Mus_musculus 0 979
ENSMUST00000146277 Grm4-003 retained_intron Mus_musculus 0 736
ENSMUST00000126890 Grm6-003 processed_transcript Mus_musculus 0 616
ENSMUST00000147865 Grm4-004 processed_transcript Mus_musculus 0 512

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