C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000555147 MC1R-001 ENSG00000258839 9606 + 16:89917879-89920977 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006AO CIL_0006AO_0002 CGP 16:89873586-89920977

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004930 IEA G-protein coupled receptor activity
GO:0004977 TAS melanocortin receptor activity
GO:0004980 IPI melanocyte-stimulating hormone receptor activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007187 TAS G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007275 TAS multicellular organismal development
GO:0008528 TAS G-protein coupled peptide receptor activity
GO:0009650 TAS UV protection
GO:0010739 ISS positive regulation of protein kinase A signaling
GO:0016021 IEA integral component of membrane
GO:0019233 IEA sensory perception of pain
GO:0030819 IDA positive regulation of cAMP biosynthetic process
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032720 IMP negative regulation of tumor necrosis factor production
GO:0035556 ISS intracellular signal transduction
GO:0042438 IEA melanin biosynthetic process
GO:0042562 IEA hormone binding
GO:0043473 TAS pigmentation
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0051897 ISS positive regulation of protein kinase B signaling
GO:0060259 IEA regulation of feeding behavior
GO:0070914 IDA UV-damage excision repair
GO:0090037 ISS positive regulation of protein kinase C signaling
GO:2000253 IEA positive regulation of feeding behavior

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000098324 Mc1r-201 protein_coding Mus_musculus 0 717

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