C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: serine/arginine-rich splicing factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000582730 SRSF1-003 ENSG00000136450 9606 - 17:58003360-58007261 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000582730
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000582730 8.993±0.00 21.904±0.00 6.289±0.00 13.608±0.00 13.201±4.83 20.168±0.34 8.080±5.14 17.747±11.91 10.739±0.00 15.760±0.12 2.117±0.00 32.773±10.79 23.260±5.76 26.467±2.98

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007PL CIL_0007PL_0001 UCNEbase 17:57406597-58005077
CIL_0009DM CIL_0009DM_0001 VISTA 17:57461902-58063720
CIL_0009DL CIL_0009DL_0001 VISTA 17:57574410-58175690

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000395 IDA mRNA 5'-splice site recognition
GO:0000398 IC mRNA splicing, via spliceosome
GO:0003676 IEA nucleic acid binding
GO:0003723 IDA RNA binding
GO:0003729 IDA mRNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006369 TAS termination of RNA polymerase II transcription
GO:0006376 TAS mRNA splice site selection
GO:0006397 TAS mRNA processing
GO:0006406 TAS mRNA export from nucleus
GO:0006417 IEA regulation of translation
GO:0008380 TAS RNA splicing
GO:0010467 TAS gene expression
GO:0016607 IDA nuclear speck
GO:0031124 TAS mRNA 3'-end processing
GO:0035145 IDA exon-exon junction complex
GO:0043488 IEA regulation of mRNA stability
GO:0044822 IDA poly(A) RNA binding
GO:0048024 IEA regulation of mRNA splicing, via spliceosome
GO:0070062 IDA extracellular vesicular exosome
GO:0071013 IDA catalytic step 2 spliceosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000079866 Srsf1-003 protein_coding Mus_musculus 0 4178
ENSMUST00000183352 SRSF1-201 protein_coding Mus_musculus 0 3203
ENSMUST00000139129 Srsf1-001 protein_coding Mus_musculus 0 3203
ENSMUST00000132983 Srsf1-004 retained_intron Mus_musculus 0 1162
ENSMUST00000134824 Srsf1-002 nonsense_mediated_decay Mus_musculus 0 832
ENSMUST00000107920 Srsf1-006 protein_coding Mus_musculus 0 804
ENSMUST00000171976 Srsf1-007 retained_intron Mus_musculus 0 523
ENSDART00000140865 srsf1b-002 protein_coding Danio_rerio 0 383
ENSDART00000110646 srsf1b-201 protein_coding Danio_rerio 0 375
ENSDART00000151683 srsf1b-003 nonsense_mediated_decay Danio_rerio 0 375
ENSDART00000143566 srsf1b-001 protein_coding Danio_rerio 0 375
ENSMUST00000172186 Srsf1-005 nonsense_mediated_decay Mus_musculus 0 270
ENSDART00000080413 srsf1a-001 protein_coding Danio_rerio 0 237
ENSDART00000133755 srsf1a-004 protein_coding Danio_rerio 0 235
ENSDART00000137058 srsf1a-003 retained_intron Danio_rerio 0 206

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