C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sphingosine kinase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000590959 SPHK1-003 ENSG00000176170 9606 + 17:76384621-76387860 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008WF CIL_0008WF_0001 VISTA 17:75822026-76422503
CIL_0001IJ CIL_0001IJ_0001 CGP 17:76274049-76384521
CIL_00009I CIL_00009I_0001 CGP 17:76309486-76387860
CIL_00079O CIL_00079O_0001 CGP 17:76376584-76453206

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 ISS magnesium ion binding
GO:0003677 IDA DNA binding
GO:0003951 IEA NAD+ kinase activity
GO:0004143 IEA diacylglycerol kinase activity
GO:0005515 IPI protein binding
GO:0005516 IDA calmodulin binding
GO:0005524 IDA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0006457 TAS protein folding
GO:0006665 TAS sphingolipid metabolic process
GO:0006670 IDA sphingosine metabolic process
GO:0007165 TAS signal transduction
GO:0007205 IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0008481 IDA sphinganine kinase activity
GO:0010803 IDA regulation of tumor necrosis factor-mediated signaling pathway
GO:0017050 IDA D-erythro-sphingosine kinase activity
GO:0019722 IDA calcium-mediated signaling
GO:0030148 TAS sphingolipid biosynthetic process
GO:0030307 IDA positive regulation of cell growth
GO:0030335 IDA positive regulation of cell migration
GO:0031398 IDA positive regulation of protein ubiquitination
GO:0035556 TAS intracellular signal transduction
GO:0042346 IMP positive regulation of NF-kappaB import into nucleus
GO:0043066 TAS negative regulation of apoptotic process
GO:0044267 TAS cellular protein metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045766 IDA positive regulation of angiogenesis
GO:0045931 IDA positive regulation of mitotic cell cycle
GO:0045987 IDA positive regulation of smooth muscle contraction
GO:0046521 NAS sphingoid catabolic process
GO:0046834 IEA lipid phosphorylation
GO:0048146 IDA positive regulation of fibroblast proliferation
GO:0051084 TAS 'de novo' posttranslational protein folding
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0051721 IPI protein phosphatase 2A binding

Homologs

No Homologs available.

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