C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: egl-9 family hypoxia-inducible factor 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000593726 EGLN2-003 ENSG00000269858 9606 + 19:40799545-40808433 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonTestisENST00000593726
Transcript ID Colon Testis
ENST00000593726 1.128±0.00 51.075±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001558 NAS regulation of cell growth
GO:0001666 IDA response to hypoxia
GO:0005506 IEA iron ion binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005829 IEA cytosol
GO:0008198 NAS ferrous iron binding
GO:0016491 IEA oxidoreductase activity
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016706 IDA:IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0018401 IDA peptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0019826 IDA oxygen sensor activity
GO:0030520 NAS intracellular estrogen receptor signaling pathway
GO:0031418 IEA L-ascorbic acid binding
GO:0031543 IEA peptidyl-proline dioxygenase activity
GO:0031545 IDA peptidyl-proline 4-dioxygenase activity
GO:0043523 IMP regulation of neuron apoptotic process
GO:0045454 IDA cell redox homeostasis
GO:0045732 IDA positive regulation of protein catabolic process
GO:0055114 IEA oxidation-reduction process
GO:0061418 TAS regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0071456 TAS cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000108382 Egln2-002 protein_coding Mus_musculus 0 1050
ENSMUST00000080058 Egln2-001 protein_coding Mus_musculus 0 1050
ENSMUST00000152021 Egln2-004 processed_transcript Mus_musculus 4e-26 124

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