C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutamate receptor, ionotropic, N-methyl D-aspartate 2B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000609686 GRIN2B-001 ENSG00000273079 9606 - 12:13537337-13980119 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLungMuscleOvaryPlacentaTestisENST00000609686
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Lung Muscle Ovary Placenta Testis
ENST00000609686 0.021±0.00 0.213±0.00 0.032±0.00 5.611±0.00 0.261±0.23 0.019±0.01 0.007±0.00 0.027±0.00 0.020±0.01 0.025±0.02 0.198±0.19 0.003±0.00 0.072±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003H7 CIL_0003H7_0001 CGP 12:13196716-13980119
CIL_0006XF CIL_0006XF_0002 CGP 12:13537337-14502935

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001662 IEA behavioral fear response
GO:0001701 IEA in utero embryonic development
GO:0001964 IEA startle response
GO:0001967 IEA suckling behavior
GO:0004970 IEA ionotropic glutamate receptor activity
GO:0004972 IBA N-methyl-D-aspartate selective glutamate receptor activity
GO:0005234 IBA:IEA extracellular-glutamate-gated ion channel activity
GO:0005261 IEA cation channel activity
GO:0005262 IEA calcium channel activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006810 TAS transport
GO:0006812 IEA cation transport
GO:0006816 IEA calcium ion transport
GO:0007215 TAS glutamate receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007423 IEA sensory organ development
GO:0007611 TAS learning or memory
GO:0007612 IEA learning
GO:0007613 IEA memory
GO:0008021 IEA synaptic vesicle
GO:0008270 ISS zinc ion binding
GO:0009986 ISS cell surface
GO:0010738 IEA regulation of protein kinase A signaling
GO:0014069 IEA postsynaptic density
GO:0016020 IEA membrane
GO:0016594 IDA glycine binding
GO:0017146 IDA N-methyl-D-aspartate selective glutamate receptor complex
GO:0030054 IEA cell junction
GO:0030425 IBA dendrite
GO:0034220 IBA ion transmembrane transport
GO:0035235 IBA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0042596 IEA fear response
GO:0043005 ISS neuron projection
GO:0045202 IEA synapse
GO:0045211 IBA postsynaptic membrane
GO:0045471 IDA response to ethanol
GO:0048167 IEA regulation of synaptic plasticity
GO:0048266 IEA behavioral response to pain
GO:0050966 IEA detection of mechanical stimulus involved in sensory perception of pain
GO:0060078 IEA regulation of postsynaptic membrane potential
GO:0060079 IEA regulation of excitatory postsynaptic membrane potential
GO:0070588 IEA calcium ion transmembrane transport
GO:0097481 IEA neuronal postsynaptic density
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000111905 Grin2b-201 protein_coding Mus_musculus 0 6545
ENSMUST00000053880 Grin2b-001 protein_coding Mus_musculus 0 6545
ENSMUST00000152012 Grin2b-002 processed_transcript Mus_musculus 0 1620
ENSDART00000047094 GRIN2B (2 of 2)-201 protein_coding Danio_rerio 0 1013
ENSDART00000103882 grin2db-201 protein_coding Danio_rerio 0 529
ENSDART00000144062 grin2db-001 protein_coding Danio_rerio 0 529
ENSMUST00000125905 Grin2b-004 protein_coding Mus_musculus 0 398
ENSMUST00000143943 Grin2b-003 protein_coding Mus_musculus 0 398
ENSMUST00000188999 Grin2b-005 protein_coding Mus_musculus 0 388

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