C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: signal peptide peptidase like 2B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000610743 SPPL2B-013 ENSG00000005206 9606 + 19:2328693-2353933 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; TestisENST00000610743
Transcript ID Testis
ENST00000610743 34.621±2.16

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001SY CIL_0001SY_0001 CGP 19:2289784-2328620
CIL_0001IB CIL_0001IB_0001 CGP 19:2321517-2354806
CIL_0003DX CIL_0003DX_0001 CGP 19:2328615-2426239

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004190 IEA aspartic-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005765 IDA lysosomal membrane
GO:0005886 IDA plasma membrane
GO:0006509 IDA membrane protein ectodomain proteolysis
GO:0010008 IDA endosome membrane
GO:0016021 IEA integral component of membrane
GO:0030660 IDA Golgi-associated vesicle membrane
GO:0031293 IDA membrane protein intracellular domain proteolysis
GO:0042500 IMP aspartic endopeptidase activity, intramembrane cleaving
GO:0042803 IDA protein homodimerization activity
GO:0050776 IMP regulation of immune response
GO:0071458 IDA integral component of cytoplasmic side of endoplasmic reticulum membrane
GO:0071556 IDA integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000035597 Sppl2b-201 protein_coding Mus_musculus 0 1458

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