C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000613098 PPARGC1A-202 ENSG00000109819 9606 - 4:23795339-23881292 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartKidneyLiverENST00000613098
Transcript ID Heart Kidney Liver
ENST00000613098 2.027±0.00 5.572±0.00 0.482±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002OU CIL_0002OU_0001 CGP 4:22345071-23904089
CIL_0007ZS CIL_0007ZS_0001 VISTA 4:23630438-24232069
CIL_00033R CIL_00033R_0002 CGP 4:23755041-24584550

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001104 TAS RNA polymerase II transcription cofactor activity
GO:0001659 TAS temperature homeostasis
GO:0001678 NAS cellular glucose homeostasis
GO:0003676 IEA nucleic acid binding
GO:0003677 ISS DNA binding
GO:0003713 IDA transcription coactivator activity
GO:0003723 TAS RNA binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005654 TAS nucleoplasm
GO:0005665 TAS DNA-directed RNA polymerase II, core complex
GO:0006094 NAS gluconeogenesis
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006397 TAS mRNA processing
GO:0006461 TAS protein complex assembly
GO:0007005 NAS mitochondrion organization
GO:0007586 TAS digestion
GO:0008134 TAS transcription factor binding
GO:0008380 TAS RNA splicing
GO:0010822 ISS positive regulation of mitochondrion organization
GO:0014850 ISS response to muscle activity
GO:0016922 IPI ligand-dependent nuclear receptor binding
GO:0019395 NAS fatty acid oxidation
GO:0022904 ISS respiratory electron transport chain
GO:0030374 IDA ligand-dependent nuclear receptor transcription coactivator activity
GO:0030521 NAS androgen receptor signaling pathway
GO:0031490 ISS chromatin DNA binding
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032922 ISS circadian regulation of gene expression
GO:0034599 ISS cellular response to oxidative stress
GO:0035066 TAS positive regulation of histone acetylation
GO:0042594 NAS response to starvation
GO:0042752 ISS regulation of circadian rhythm
GO:0043524 ISS negative regulation of neuron apoptotic process
GO:0043565 IDA sequence-specific DNA binding
GO:0045333 TAS cellular respiration
GO:0045722 TAS positive regulation of gluconeogenesis
GO:0045893 NAS positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046321 TAS positive regulation of fatty acid oxidation
GO:0050681 NAS androgen receptor binding
GO:0050821 TAS protein stabilization
GO:0050873 TAS brown fat cell differentiation
GO:0051091 IDA positive regulation of sequence-specific DNA binding transcription factor activity
GO:1901215 IGI negative regulation of neuron death
GO:2000507 ISS positive regulation of energy homeostasis
GO:2001171 ISS positive regulation of ATP biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000132734 Ppargc1a-001 protein_coding Mus_musculus 0 3520
ENSMUST00000031059 Ppargc1a-002 nonsense_mediated_decay Mus_musculus 0 2453
ENSMUST00000151104 Ppargc1a-003 protein_coding Mus_musculus 0 822
ENSMUST00000127135 Ppargc1a-004 protein_coding Mus_musculus 1e-31 143

Loading