C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: paired-like homeodomain 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000614423 PITX2-202 ENSG00000164093 9606 - 4:110617428-110642123 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000917 CIL_000917_0001 VISTA 4:110309018-110909617
CIL_000912 CIL_000912_0001 VISTA 4:110357117-110957671
CIL_0007ZJ CIL_0007ZJ_0001 VISTA 4:110448103-111050012
CIL_0007RD CIL_0007RD_0001 VISTA 4:110613299-111214576

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000976 IDA transcription regulatory region sequence-specific DNA binding
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001105 IDA RNA polymerase II transcription coactivator activity
GO:0001191 IDA RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription
GO:0003253 ISS cardiac neural crest cell migration involved in outflow tract morphogenesis
GO:0003677 IEA DNA binding
GO:0003700 IEA:IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0006355 IEA:IDA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0007368 ISS determination of left/right symmetry
GO:0008134 IPI transcription factor binding
GO:0035315 IC hair cell differentiation
GO:0035993 IMP deltoid tuberosity development
GO:0042476 IMP odontogenesis
GO:0042803 IPI protein homodimerization activity
GO:0043010 IMP camera-type eye development
GO:0043021 IC ribonucleoprotein complex binding
GO:0043565 IEA sequence-specific DNA binding
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048536 ISS spleen development
GO:0051219 IPI phosphoprotein binding
GO:0060126 TAS somatotropin secreting cell differentiation
GO:0060127 TAS prolactin secreting cell differentiation
GO:0061072 IMP iris morphogenesis
GO:0061325 ISS cell proliferation involved in outflow tract morphogenesis
GO:0070986 ISS left/right axis specification

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000174661 Pitx2-002 protein_coding Mus_musculus 0 2231
ENSMUST00000042587 Pitx2-003 protein_coding Mus_musculus 0 1962
ENSMUST00000106382 Pitx2-001 protein_coding Mus_musculus 0 1962
ENSMUST00000029657 Pitx2-005 protein_coding Mus_musculus 0 1666
ENSMUST00000172645 Pitx2-006 protein_coding Mus_musculus 0 1243
ENSMUST00000174623 Pitx2-004 protein_coding Mus_musculus 0 287
ENSMUST00000187145 Pitx2-007 retained_intron Mus_musculus 0 287
ENSMUST00000173645 Pitx2-008 protein_coding Mus_musculus 0 270

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