C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: a disintegrin and metalloproteinase domain 8a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000001452 adam8a 7955 + 13:24895371-24903526 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000001678 adam8a-001 24895371-24903526 protein_coding
  ENSDART00000139572 adam8a-002 24899714-24900910 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000001678ENSDART00000139572
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000001678 0.336±0.12 2.887±1.17 15.209±13.05 0.235±0.00 4.420±0.00
ENSDART00000139572 0.490±0.03 2.223±0.00 N/A 0.275±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002020 IPI protease binding
GO:0004222 IEA metalloendopeptidase activity
GO:0005515 IEA protein binding
GO:0006508 IEA proteolysis
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008237 IEA metallopeptidase activity
GO:0008270 IEA zinc ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000151651 ADAM8 ADAM metallopeptidase domain 8 protein_coding Homo_sapiens
ENSMUSG00000025473 Adam8 a disintegrin and metallopeptidase domain 8 protein_coding Mus_musculus

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