C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hairy/enhancer-of-split related with YRPW motif 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000013441 hey2 7955 - 20:39614606-39622047 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000023531 hey2-001 39614606-39622047 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000023531
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000023531 2.413±0.41 12.065±7.02 3.630±2.83 0.051±0.00 1.267±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001568 IMP blood vessel development
GO:0001570 IMP vasculogenesis
GO:0003677 IEA DNA binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0007219 IEA Notch signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0007507 IMP heart development
GO:0035912 IMP dorsal aorta morphogenesis
GO:0045892 IGI negative regulation of transcription, DNA-dependent
GO:0046983 IEA protein dimerization activity
GO:0048514 IMP blood vessel morphogenesis
GO:0048844 IMP artery morphogenesis
GO:0060853 IMP Notch signaling pathway involved in arterial endothelial cell fate commitment

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000135547 HEY2 hes-related family bHLH transcription factor with YRPW motif 2 protein_coding Homo_sapiens
ENSMUSG00000019789 Hey2 hairy/enhancer-of-split related with YRPW motif 2 protein_coding Mus_musculus

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