C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: toll-like receptor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000016065 tlr3 7955 + 1:16634839-16640122 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000013021 tlr3-001 16634839-16640122 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000013021
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000013021 0.416±0.21 1.979±0.42 0.809±0.05 0.246±0.00 0.355±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000H1 CIL_0000H1_0001 CGP 1:16489551-16640122

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001819 IEA positive regulation of cytokine production
GO:0002756 IEA MyD88-independent toll-like receptor signaling pathway
GO:0003725 IEA double-stranded RNA binding
GO:0004888 IEA transmembrane signaling receptor activity
GO:0005515 IPI protein binding
GO:0007165 IEA signal transduction
GO:0009615 IDA response to virus
GO:0009617 IDA response to bacterium
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0032722 IEA positive regulation of chemokine production
GO:0034138 IEA toll-like receptor 3 signaling pathway
GO:0043330 IEA response to exogenous dsRNA
GO:0045087 IEA innate immune response
GO:0050729 IEA positive regulation of inflammatory response
GO:0051607 IEA defense response to virus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000164342 TLR3 toll-like receptor 3 protein_coding Homo_sapiens
ENSMUSG00000031639 Tlr3 toll-like receptor 3 protein_coding Mus_musculus

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