C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SMAD specific E3 ubiquitin protein ligase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000016086 smurf1 7955 - 3:40684994-40763330 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000004923 smurf1-001 40684994-40763330 protein_coding
  ENSDART00000129705 smurf1-201 40684997-40763139 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000004923ENSDART00000129705
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000004923 5.883±3.62 1.552±0.06 2.050±1.21 2.152±0.00 2.545±0.00
ENSDART00000129705 N/A 0.535±0.16 1.028±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004842 IEA ubiquitin-protein ligase activity
GO:0005515 IEA protein binding
GO:0005634 IBA nucleus
GO:0005737 IBA cytoplasm
GO:0007179 IBA transforming growth factor beta receptor signaling pathway
GO:0016874 IEA ligase activity
GO:0042787 IBA protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000198742 SMURF1 SMAD specific E3 ubiquitin protein ligase 1 protein_coding Homo_sapiens
ENSMUSG00000038780 Smurf1 SMAD specific E3 ubiquitin protein ligase 1 protein_coding Mus_musculus

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