C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mutS homolog 2 (E. coli)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000018022 msh2 7955 - 12:26412446-26434837 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000002465 msh2-001 26412446-26434837 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000002465
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000002465 5.580±0.11 1.821±1.14 5.917±4.62 0.341±0.00 1.513±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000228 IBA nuclear chromosome
GO:0000400 IBA four-way junction DNA binding
GO:0000403 IBA Y-form DNA binding
GO:0000404 IBA loop DNA binding
GO:0000406 IBA double-strand/single-strand DNA junction binding
GO:0000710 IBA meiotic mismatch repair
GO:0003684 IBA damaged DNA binding
GO:0005524 IEA ATP binding
GO:0006200 IBA ATP catabolic process
GO:0006298 IEA mismatch repair
GO:0006301 IBA postreplication repair
GO:0006302 IBA double-strand break repair
GO:0006311 IBA meiotic gene conversion
GO:0008094 IBA DNA-dependent ATPase activity
GO:0010165 IBA response to X-ray
GO:0010224 IBA response to UV-B
GO:0016446 IBA somatic hypermutation of immunoglobulin genes
GO:0030983 IEA mismatched DNA binding
GO:0031573 IBA intra-S DNA damage checkpoint
GO:0032137 IDA guanine/thymine mispair binding
GO:0032138 IBA single base insertion or deletion binding
GO:0032301 IEA MutSalpha complex
GO:0032302 IEA MutSbeta complex
GO:0042771 IBA intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043570 IMP maintenance of DNA repeat elements
GO:0045128 IBA negative regulation of reciprocal meiotic recombination
GO:0045190 IBA isotype switching

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000095002 MSH2 mutS homolog 2 protein_coding Homo_sapiens
ENSMUSG00000024151 Msh2 mutS homolog 2 (E. coli) protein_coding Mus_musculus

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