C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NK2 transcription factor related 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000021232 nkx2.7 7955 + 8:52507261-52510351 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000023639 nkx2.7-001 52507261-52510351 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartKidneyENSDART00000023639
Transcript ID Heart Kidney
ENSDART00000023639 0.501±0.45 0.061±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006NB CIL_0006NB_0001 CGP 8:52448964-52510351
CIL_0005R4 CIL_0005R4_0001 CGP 8:52507261-52538280

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001947 IMP heart looping
GO:0003007 IGI heart morphogenesis
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005634 IEA nucleus
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0035050 IMP embryonic heart tube development
GO:0043565 IEA sequence-specific DNA binding
GO:0055007 IMP cardiac muscle cell differentiation
GO:0060038 IGI cardiac muscle cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000180053 NKX2-6 NK2 homeobox 6 protein_coding Homo_sapiens
ENSMUSG00000044186 Nkx2-6 NK2 homeobox 6 protein_coding Mus_musculus

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