C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: denticleless homolog (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000023002 dtl 7955 + 20:13056182-13088939 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000034098 dtl-001 13056182-13088939 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000034098
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000034098 0.158±0.06 0.202±0.13 11.785±3.78 0.258±0.00 0.112±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000128 CIL_000128_0001 CGP 20:12935263-13088939
CIL_000129 CIL_000129_0001 CGP 20:13056182-13226692

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000209 ISS protein polyubiquitination
GO:0004842 ISS ubiquitin-protein ligase activity
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005694 IEA chromosome
GO:0005737 IEA cytoplasm
GO:0005813 ISS centrosome
GO:0005856 IEA cytoskeleton
GO:0006260 IEA DNA replication
GO:0006511 ISS ubiquitin-dependent protein catabolic process
GO:0006513 ISS protein monoubiquitination
GO:0006974 ISS cellular response to DNA damage stimulus
GO:0007095 IMP mitotic G2 DNA damage checkpoint
GO:0009411 ISS response to UV
GO:0019985 ISS translesion synthesis
GO:0031464 ISS Cul4A-RING ubiquitin ligase complex
GO:0031465 ISS Cul4B-RING ubiquitin ligase complex
GO:0051726 ISS regulation of cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000143476 DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) protein_coding Homo_sapiens
ENSMUSG00000037474 Dtl denticleless homolog (Drosophila) protein_coding Mus_musculus

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