C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lethal giant larvae homolog 2 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000023920 llgl2 7955 - 12:35233271-35283975 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000034550 llgl2-201 35233271-35283975 protein_coding
  ENSDART00000127203 llgl2-004 35233732-35241019 protein_coding
  ENSDART00000132047 llgl2-002 35236615-35240919 retained_intron
  ENSDART00000138776 llgl2-003 35233900-35236653 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000034550ENSDART00000127203
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000034550 2.221±0.28 5.817±1.65 5.179±0.88 1.667±0.00 0.785±0.00
ENSDART00000127203 N/A 9.745±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0006887 IEA exocytosis
GO:0007010 IMP cytoskeleton organization
GO:0007049 IEA cell cycle
GO:0008285 IMP negative regulation of cell proliferation
GO:0008544 IMP epidermis development
GO:0010719 IMP negative regulation of epithelial to mesenchymal transition
GO:0030336 IMP negative regulation of cell migration
GO:0031581 IMP hemidesmosome assembly
GO:0043588 IMP skin development
GO:0045682 IGI regulation of epidermis development
GO:0048919 IMP posterior lateral line neuromast development
GO:0050680 IMP negative regulation of epithelial cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000073350 LLGL2 lethal giant larvae homolog 2 (Drosophila) protein_coding Homo_sapiens
ENSMUSG00000020782 Llgl2 lethal giant larvae homolog 2 (Drosophila) protein_coding Mus_musculus

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