C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: spastin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000024933 spast 7955 - 1:51530601-51548207 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000035150 spast-001 51530601-51548207 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000035150
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000035150 6.877±1.15 2.705±0.97 1.544±0.22 0.549±0.00 2.385±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001578 ISS microtubule bundle formation
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005813 IEA centrosome
GO:0005856 IEA cytoskeleton
GO:0005874 IEA microtubule
GO:0006200 ISS ATP catabolic process
GO:0006281 IEA DNA repair
GO:0006310 IEA DNA recombination
GO:0007049 IEA cell cycle
GO:0007275 IEA multicellular organismal development
GO:0007399 IEA nervous system development
GO:0008017 ISS microtubule binding
GO:0008568 IEA microtubule-severing ATPase activity
GO:0009378 IEA four-way junction helicase activity
GO:0015630 ISS microtubule cytoskeleton
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0016787 IEA hydrolase activity
GO:0017111 IEA nucleoside-triphosphatase activity
GO:0021955 IMP central nervous system neuron axonogenesis
GO:0030154 IEA cell differentiation
GO:0031117 IMP positive regulation of microtubule depolymerization
GO:0031122 IMP cytoplasmic microtubule organization
GO:0034214 ISS protein hexamerization
GO:0043014 ISS alpha-tubulin binding
GO:0043066 IMP negative regulation of apoptotic process
GO:0045773 IMP positive regulation of axon extension
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048487 ISS beta-tubulin binding
GO:0048675 IGI axon extension
GO:0051013 ISS microtubule severing
GO:0051260 ISS protein homooligomerization
GO:0051301 IEA cell division

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000021574 SPAST spastin protein_coding Homo_sapiens
ENSMUSG00000024068 Spast spastin protein_coding Mus_musculus

Loading