C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: seven in absentia homolog 1 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000030871 siah1 7955 + 18:18098500-18131424 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000043843 siah1-201 18098500-18131424 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000043843
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000043843 10.330±3.41 7.225±8.15 2.280±0.25 0.800±0.00 5.657±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IEA ubiquitin-protein ligase activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005829 ISS cytosol
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0007275 IEA multicellular organismal development
GO:0008270 IEA zinc ion binding
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0042787 ISS protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043161 ISS proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0046872 IEA metal ion binding
GO:0051402 ISS neuron apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000196470 SIAH1 siah E3 ubiquitin protein ligase 1 protein_coding Homo_sapiens
ENSMUSG00000036840 Siah1a seven in absentia 1A protein_coding Mus_musculus
ENSMUSG00000040749 Siah1b seven in absentia 1B protein_coding Mus_musculus

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