C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: insulin-like growth factor 1b receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000034434 igf1rb 7955 + 7:16215786-16373369 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000046542 igf1rb-001 16215786-16373369 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000046542
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000046542 1.073±0.69 1.928±1.68 3.937±1.94 0.073±0.00 0.744±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0003007 IGI heart morphogenesis
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005515 IEA protein binding
GO:0005520 IPI insulin-like growth factor binding
GO:0005524 IEA ATP binding
GO:0006468 IEA protein phosphorylation
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007507 IMP heart development
GO:0008354 IMP germ cell migration
GO:0009790 IMP embryo development
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016740 IEA transferase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 ISS peptidyl-tyrosine phosphorylation
GO:0021522 IMP spinal cord motor neuron differentiation
GO:0031076 IGI embryonic camera-type eye development
GO:0031101 IMP fin regeneration
GO:0043010 IMP camera-type eye development
GO:0043027 IGI cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043154 IGI negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043548 IEA phosphatidylinositol 3-kinase binding
GO:0043560 IEA insulin receptor substrate binding
GO:0046777 IEA protein autophosphorylation
GO:0048009 IDA insulin-like growth factor receptor signaling pathway
GO:0048752 IMP semicircular canal morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000140443 IGF1R insulin-like growth factor 1 receptor protein_coding Homo_sapiens
ENSMUSG00000005533 Igf1r insulin-like growth factor I receptor protein_coding Mus_musculus

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