C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: parkinson disease (autosomal recessive, early onset) 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000034826 park7 7955 + 11:42557105-42571428 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000041531 park7-001 42557105-42571428 protein_coding
  ENSDART00000140011 park7-002 42557139-42571428 protein_coding
  ENSDART00000147834 park7-003 42557123-42571016 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000041531ENSDART00000140011
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000041531 34.692±21.37 74.610±2.24 50.633±18.57 4.645±0.00 56.090±0.00
ENSDART00000140011 6.865±2.31 N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003723 IEA RNA binding
GO:0003729 ISS mRNA binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005739 ISS mitochondrion
GO:0006508 IEA proteolysis
GO:0006914 IEA autophagy
GO:0006950 IEA response to stress
GO:0006954 IEA inflammatory response
GO:0006979 IMP response to oxidative stress
GO:0007338 IEA single fertilization
GO:0008233 ISS peptidase activity
GO:0016787 IEA hydrolase activity
GO:0034599 ISS cellular response to oxidative stress
GO:0042803 ISS protein homodimerization activity
GO:0043523 ISS regulation of neuron apoptotic process
GO:0050821 ISS protein stabilization
GO:0060548 ISS negative regulation of cell death
GO:0070301 ISS cellular response to hydrogen peroxide
GO:2000277 ISS positive regulation of oxidative phosphorylation uncoupler activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000116288 PARK7 parkinson protein 7 protein_coding Homo_sapiens
ENSMUSG00000028964 Park7 Parkinson disease (autosomal recessive, early onset) 7 protein_coding Mus_musculus

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