C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: connexin 43
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000041799 cx43 7955 - 20:40746894-40752261 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000047272 cx43-201 40746895-40752261 protein_coding
  ENSDART00000061261 cx43-001 40746894-40752252 protein_coding
  ENSDART00000138569 cx43-002 40746894-40752261 protein_coding
  ENSDART00000153151 cx43-003 40748618-40752189 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000047272ENSDART00000061261ENSDART00000138569ENSDART00000153151
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000047272 251.275±9.44 N/A 1.046±0.00 N/A N/A
ENSDART00000061261 233.156±68.25 4.152±1.28 3.550±0.00 1.156±0.00 14.997±0.00
ENSDART00000138569 27.187±0.00 1.178±0.00 1.097±0.00 N/A N/A
ENSDART00000153151 N/A N/A N/A 0.478±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005243 IDA gap junction channel activity
GO:0005886 IDA plasma membrane
GO:0005921 IDA gap junction
GO:0005922 IEA connexon complex
GO:0007154 IEA cell communication
GO:0007267 IEA cell-cell signaling
GO:0007275 IEA multicellular organismal development
GO:0007507 IEA heart development
GO:0008283 IMP cell proliferation
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0022832 IDA voltage-gated channel activity
GO:0022857 IEA transmembrane transporter activity
GO:0030054 IEA cell junction
GO:0030154 IEA cell differentiation
GO:0031101 IMP fin regeneration
GO:0035050 IMP embryonic heart tube development
GO:0035143 IMP caudal fin morphogenesis
GO:0035162 IMP embryonic hemopoiesis
GO:0051049 IDA regulation of transport
GO:0055077 IDA gap junction hemi-channel activity
GO:0055085 IDA transmembrane transport
GO:0060272 IMP embryonic skeletal joint morphogenesis
GO:0070121 IMP Kupffer's vesicle development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000152661 GJA1 gap junction protein, alpha 1, 43kDa protein_coding Homo_sapiens
ENSMUSG00000050953 Gja1 gap junction protein, alpha 1 protein_coding Mus_musculus
ENSMUSG00000055691 Gja6 gap junction protein, alpha 6 protein_coding Mus_musculus

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