C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: a disintegrin and metalloproteinase domain 17a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000043213 adam17a 7955 - 17:35414627-35445893 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000063437 adam17a-001 35414627-35445893 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000063437
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000063437 10.543±2.41 11.859±5.61 7.287±1.77 1.208±0.00 3.372±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007AU CIL_0007AU_0001 CGP 17:35410883-35445893

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004222 IEA metalloendopeptidase activity
GO:0006508 IEA proteolysis
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008233 IEA peptidase activity
GO:0008237 IEA metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0016787 IEA hydrolase activity
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000151694 ADAM17 ADAM metallopeptidase domain 17 protein_coding Homo_sapiens
ENSMUSG00000052593 Adam17 a disintegrin and metallopeptidase domain 17 protein_coding Mus_musculus

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