C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: O-6-methylguanine-DNA methyltransferase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000043275 mgmt 7955 - 17:20044366-20048544 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000063523 mgmt-001 20044366-20048544 protein_coding
  ENSDART00000154479 mgmt-004 20044717-20048320 protein_coding
  ENSDART00000155632 mgmt-005 20044479-20048522 protein_coding
  ENSDART00000155990 mgmt-003 20044680-20048510 protein_coding
  ENSDART00000156540 mgmt-002 20044656-20048522 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000063523ENSDART00000154479ENSDART00000155632ENSDART00000155990ENSDART00000156540
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000063523 1.734±1.03 2.613±1.69 6.369±1.85 N/A N/A
ENSDART00000154479 2.244±0.00 2.990±0.00 N/A N/A N/A
ENSDART00000155632 1.071±0.51 N/A 1.757±0.00 N/A N/A
ENSDART00000155990 N/A 2.133±0.00 2.509±0.00 N/A N/A
ENSDART00000156540 1.897±0.37 2.685±0.25 5.513±0.00 0.859±0.00 0.673±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0003908 IEA methylated-DNA-[protein]-cysteine S-methyltransferase activity
GO:0006281 IEA DNA repair

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000170430 MGMT O-6-methylguanine-DNA methyltransferase protein_coding Homo_sapiens
ENSMUSG00000054612 Mgmt O-6-methylguanine-DNA methyltransferase protein_coding Mus_musculus

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