C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysyl oxidase-like 2a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000044010 loxl2a 7955 - 10:20489093-20526754 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000064613 loxl2a-201 20489093-20526754 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverENSDART00000064613
Transcript ID Brain Heart Kidney Liver
ENSDART00000064613 0.080±0.00 0.822±0.47 0.982±0.00 2.062±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 ISS response to hypoxia
GO:0001837 ISS epithelial to mesenchymal transition
GO:0001935 ISS endothelial cell proliferation
GO:0002040 IMP sprouting angiogenesis
GO:0004720 IEA protein-lysine 6-oxidase activity
GO:0005044 IEA scavenger receptor activity
GO:0005507 IEA copper ion binding
GO:0005576 IEA extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005604 ISS basement membrane
GO:0005634 IEA nucleus
GO:0005694 IEA chromosome
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0016020 IEA membrane
GO:0016491 IEA oxidoreductase activity
GO:0016568 IEA chromatin modification
GO:0016641 IEA oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
GO:0030199 ISS collagen fibril organization
GO:0032332 ISS positive regulation of chondrocyte differentiation
GO:0043542 ISS endothelial cell migration
GO:0045892 ISS negative regulation of transcription, DNA-dependent
GO:0046872 IEA metal ion binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000134013 LOXL2 lysyl oxidase-like 2 protein_coding Homo_sapiens
ENSMUSG00000034205 Loxl2 lysyl oxidase-like 2 protein_coding Mus_musculus

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