C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysyl oxidase-like 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034205 Loxl2 10090 + 14:69609068-69695834 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022660 Loxl2-001 69609068-69695834 protein_coding
  ENSMUST00000100420 Loxl2-002 69609478-69693698 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022660
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022660 13.649±8.41 2.326±0.21 18.293±2.80 1.926±1.59 12.439±6.75 7.203±0.48 3.939±0.73 4.066±0.20 1.554±1.16 3.919±0.15 1.364±0.26 13.203±1.81 10.348±4.94 0.327±0.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007YD CIL_0007YD_0002 VISTA 14:69222690-69823937
CIL_0008FQ CIL_0008FQ_0002 VISTA 14:69236074-69837250

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IDA response to hypoxia
GO:0001837 ISS epithelial to mesenchymal transition
GO:0001935 ISS endothelial cell proliferation
GO:0002040 ISS sprouting angiogenesis
GO:0003682 ISS chromatin binding
GO:0003714 ISS transcription corepressor activity
GO:0004720 ISS protein-lysine 6-oxidase activity
GO:0005044 IEA scavenger receptor activity
GO:0005507 IEA copper ion binding
GO:0005515 IEA protein binding
GO:0005604 ISS basement membrane
GO:0005615 ISS extracellular space
GO:0005634 ISS nucleus
GO:0005694 IEA chromosome
GO:0006351 IEA transcription, DNA-templated
GO:0006464 ISS cellular protein modification process
GO:0006898 IEA receptor-mediated endocytosis
GO:0016020 IEA membrane
GO:0016570 ISS histone modification
GO:0018277 ISS protein deamination
GO:0030199 ISS collagen fibril organization
GO:0032332 IMP positive regulation of chondrocyte differentiation
GO:0035064 ISS methylated histone binding
GO:0043542 ISS endothelial cell migration
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0046688 ISS response to copper ion
GO:0055114 ISS oxidation-reduction process
GO:0070492 ISS oligosaccharide binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044010 loxl2a lysyl oxidase-like 2a protein_coding Danio_rerio
ENSDARG00000044074 loxl2b lysyl oxidase-like 2b protein_coding Danio_rerio
ENSDARG00000091492 LOXL2 (3 of 3) lysyl oxidase-like 2 protein_coding Danio_rerio
ENSG00000134013 LOXL2 lysyl oxidase-like 2 protein_coding Homo_sapiens

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