C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: activin receptor IIb
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000044422 acvr2b 7955 - 24:42914072-42967441 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000019975 acvr2b-201 42914072-42927052 protein_coding
  ENSDART00000121592 acvr2b-202 42914072-42927052 protein_coding
  ENSDART00000150207 acvr2b-001 42926843-42967441 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000019975ENSDART00000121592ENSDART00000150207
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000019975 N/A 0.183±0.00 N/A 1.664±0.00 0.196±0.00
ENSDART00000121592 N/A 0.263±0.00 N/A N/A N/A
ENSDART00000150207 0.842±0.73 0.805±0.38 1.249±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001501 IMP skeletal system development
GO:0001755 IMP neural crest cell migration
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004675 IEA transmembrane receptor protein serine/threonine kinase activity
GO:0004702 IEA receptor signaling protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005024 IEA transforming growth factor beta-activated receptor activity
GO:0005524 IEA ATP binding
GO:0006468 IEA protein phosphorylation
GO:0007178 IEA transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030902 IMP hindbrain development
GO:0051216 IMP cartilage development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000114739 ACVR2B activin A receptor, type IIB protein_coding Homo_sapiens
ENSMUSG00000061393 Acvr2b activin receptor IIB protein_coding Mus_musculus

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