C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CDGSH iron sulfur domain 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000052703 cisd2 7955 + 1:44068771-44074661 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000074604 cisd2-001 44068771-44074661 protein_coding
  ENSDART00000137791 cisd2-002 44068855-44071101 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000074604ENSDART00000137791
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000074604 3.467±0.61 3.583±1.48 7.103±1.94 0.357±0.00 0.576±0.00
ENSDART00000137791 0.775±0.00 N/A N/A N/A 0.444±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002K0 CIL_0002K0_0001 CGP 1:44068771-44094640

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000422 ISS mitochondrion degradation
GO:0005739 IEA mitochondrion
GO:0005741 ISS mitochondrial outer membrane
GO:0005783 IEA endoplasmic reticulum
GO:0005789 ISS endoplasmic reticulum membrane
GO:0006914 IEA autophagy
GO:0010259 ISS multicellular organismal aging
GO:0010506 ISS regulation of autophagy
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0042803 ISS protein homodimerization activity
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0046872 IEA metal ion binding
GO:0051536 IEA iron-sulfur cluster binding
GO:0051537 IEA 2 iron, 2 sulfur cluster binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000145354 CISD2 CDGSH iron sulfur domain 2 protein_coding Homo_sapiens
ENSMUSG00000028165 Cisd2 CDGSH iron sulfur domain 2 protein_coding Mus_musculus

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