C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CDGSH iron sulfur domain 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000145354 CISD2 9606 + 4:102868978-102889242 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000273986 CISD2-001 102868978-102889242 protein_coding
  ENST00000503643 CISD2-002 102869336-102887756 protein_coding
  ENST00000574446 CISD2-005 102869054-102887359 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000273986ENST00000503643ENST00000574446
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000273986 0.484±0.00 7.929±3.40 1.489±0.75 2.007±0.47 1.236±0.09 2.735±0.06 2.627±0.71 1.775±1.00 1.993±0.00 4.760±2.14 2.878±0.57 5.575±2.99
ENST00000503643 N/A N/A N/A N/A N/A N/A N/A N/A 0.473±0.00 1.777±0.00 N/A N/A
ENST00000574446 N/A N/A N/A N/A N/A N/A N/A N/A 0.700±0.00 2.785±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002K0 CIL_0002K0_0002 CGP 4:102868978-103019739

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000422 IEA mitochondrion degradation
GO:0005515 IPI protein binding
GO:0005741 ISS mitochondrial outer membrane
GO:0005783 IDA endoplasmic reticulum
GO:0005789 IDA endoplasmic reticulum membrane
GO:0010259 ISS multicellular organismal aging
GO:0010506 IMP regulation of autophagy
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0042803 IDA protein homodimerization activity
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043234 IDA protein complex
GO:0044822 IDA poly(A) RNA binding
GO:0046872 IEA metal ion binding
GO:0051537 IDA:IEA 2 iron, 2 sulfur cluster binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052703 cisd2 CDGSH iron sulfur domain 2 protein_coding Danio_rerio
ENSMUSG00000028165 Cisd2 CDGSH iron sulfur domain 2 protein_coding Mus_musculus

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