C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: methylenetetrahydrofolate reductase (NAD(P)H)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000053087 mthfr 7955 + 8:49375246-49408678 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000075068 mthfr-201 49377290-49408678 protein_coding
  ENSDART00000146018 mthfr-001 49375246-49407221 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyMuscleENSDART00000075068ENSDART00000146018
Transcript ID Brain Heart Kidney Muscle
ENSDART00000075068 1.814±1.23 4.214±3.04 3.532±2.00 1.160±0.00
ENSDART00000146018 0.700±0.00 0.693±0.31 1.152±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004489 IEA methylenetetrahydrofolate reductase (NAD(P)H) activity
GO:0005575 ND cellular_component
GO:0006555 IEA methionine metabolic process
GO:0016491 IEA oxidoreductase activity
GO:0035999 IEA tetrahydrofolate interconversion
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000177000 MTHFR methylenetetrahydrofolate reductase (NAD(P)H) protein_coding Homo_sapiens
ENSMUSG00000029009 Mthfr 5,10-methylenetetrahydrofolate reductase protein_coding Mus_musculus

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