C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: frizzled homolog 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000054438 fzd2 7955 + 3:31758750-31761189 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000076636 fzd2-001 31758750-31761189 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000076636
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000076636 3.004±1.50 19.048±13.47 4.328±0.00 0.527±0.00 2.416±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001944 IBA vasculature development
GO:0001947 IMP heart looping
GO:0003146 IMP heart jogging
GO:0004871 IEA signal transducer activity
GO:0004888 IEA transmembrane signaling receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005515 IEA protein binding
GO:0005737 IBA cytoplasm
GO:0005886 IDA plasma membrane
GO:0007165 IEA signal transduction
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007199 IBA G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
GO:0007223 IGI Wnt receptor signaling pathway, calcium modulating pathway
GO:0007275 IEA multicellular organismal development
GO:0007368 IGI determination of left/right symmetry
GO:0007409 IBA axonogenesis
GO:0007420 IBA brain development
GO:0008406 IBA gonad development
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0016055 IEA Wnt receptor signaling pathway
GO:0016477 IMP cell migration
GO:0017147 IBA Wnt-protein binding
GO:0030165 IBA PDZ domain binding
GO:0030855 IBA epithelial cell differentiation
GO:0031018 IMP endocrine pancreas development
GO:0032589 IBA neuron projection membrane
GO:0042384 IMP cilium assembly
GO:0042813 IEA Wnt-activated receptor activity
GO:0045177 IBA apical part of cell
GO:0060027 IMP convergent extension involved in gastrulation
GO:0060070 IBA canonical Wnt receptor signaling pathway
GO:0061341 IMP non-canonical Wnt receptor signaling pathway involved in heart development
GO:0070654 IEP sensory epithelium regeneration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000180340 FZD2 frizzled class receptor 2 protein_coding Homo_sapiens
ENSMUSG00000050288 Fzd2 frizzled homolog 2 (Drosophila) protein_coding Mus_musculus

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