C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: frizzled class receptor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000180340 FZD2 9606 + 17:44557459-44559570 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000315323 FZD2-001 44557459-44559570 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000315323
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000315323 0.962±0.00 1.207±0.00 0.191±0.00 0.772±0.00 0.663±0.00 0.567±0.00 2.908±0.00 0.385±0.21 0.669±0.41 0.297±0.00 6.309±2.42 5.660±1.89 1.897±0.78

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009B6 CIL_0009B6_0001 VISTA 17:43966083-44567774
CIL_0007ST CIL_0007ST_0001 VISTA 17:44247434-44848646
CIL_0005IY CIL_0005IY_0001 CGP 17:44557459-44690308

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001944 IBA vasculature development
GO:0003149 IEA membranous septum morphogenesis
GO:0003150 IEA muscular septum morphogenesis
GO:0003151 IEA outflow tract morphogenesis
GO:0004888 IEA transmembrane signaling receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007199 IBA G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
GO:0007223 IBA Wnt signaling pathway, calcium modulating pathway
GO:0007267 IEA cell-cell signaling
GO:0007409 IBA axonogenesis
GO:0007420 IBA brain development
GO:0007608 IEA sensory perception of smell
GO:0008406 IBA gonad development
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0017147 IBA Wnt-protein binding
GO:0030165 IPI PDZ domain binding
GO:0030182 ISS neuron differentiation
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0030825 IMP positive regulation of cGMP metabolic process
GO:0030855 IBA epithelial cell differentiation
GO:0032589 IBA neuron projection membrane
GO:0042813 IBA Wnt-activated receptor activity
GO:0045177 IBA apical part of cell
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0051091 IDA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060022 IEA hard palate development
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060119 IEA inner ear receptor cell development
GO:0060412 IEA ventricular septum morphogenesis
GO:0090103 IEA cochlea morphogenesis
GO:0090179 IEA planar cell polarity pathway involved in neural tube closure

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054438 fzd2 frizzled homolog 2 protein_coding Danio_rerio
ENSMUSG00000050288 Fzd2 frizzled homolog 2 (Drosophila) protein_coding Mus_musculus

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