C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: prostaglandin I2 (prostacyclin) synthase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000060094 ptgis 7955 - 6:46505303-46526910 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000084334 ptgis-001 46505303-46526910 protein_coding
  ENSDART00000127906 ptgis-002 46505318-46508613 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000084334
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000084334 0.560±0.19 0.548±0.02 1.482±0.00 0.119±0.00 0.294±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006IT CIL_0006IT_0001 CGP 6:46444793-46526910

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004497 IEA monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0008116 IEA prostaglandin-I synthase activity
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016853 IEA isomerase activity
GO:0020037 IEA heme binding
GO:0046872 IEA metal ion binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000124212 PTGIS prostaglandin I2 (prostacyclin) synthase protein_coding Homo_sapiens
ENSMUSG00000017969 Ptgis prostaglandin I2 (prostacyclin) synthase protein_coding Mus_musculus

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