C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphoinositide-3-kinase, class 2, alpha polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000060841 pik3c2a 7955 + 18:26945482-27017504 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000086131 pik3c2a-201 26951638-27016589 protein_coding
  ENSDART00000133547 pik3c2a-001 26945482-27017504 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartLiverMuscleENSDART00000086131ENSDART00000133547
Transcript ID Brain Heart Liver Muscle
ENSDART00000086131 N/A N/A 0.404±0.00 N/A
ENSDART00000133547 3.151±1.50 18.342±10.99 1.489±0.00 2.506±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0005488 IEA binding
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005886 IBA plasma membrane
GO:0005942 IBA phosphatidylinositol 3-kinase complex
GO:0007154 IEA cell communication
GO:0016301 IEA kinase activity
GO:0016303 IBA 1-phosphatidylinositol-3-kinase activity
GO:0016310 IEA phosphorylation
GO:0016740 IEA transferase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0035005 IBA 1-phosphatidylinositol-4-phosphate 3-kinase activity
GO:0035091 IEA phosphatidylinositol binding
GO:0036092 IBA phosphatidylinositol-3-phosphate biosynthetic process
GO:0046854 IEA phosphatidylinositol phosphorylation
GO:0048015 IEA phosphatidylinositol-mediated signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000011405 PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha protein_coding Homo_sapiens
ENSMUSG00000030660 Pik3c2a phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide protein_coding Mus_musculus

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