C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000011405 PIK3C2A 9606 - 11:17077730-17207983 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265970 PIK3C2A-001 17086572-17169741 protein_coding
  ENST00000503729 PIK3C2A-004 17194394-17207983 processed_transcript
  ENST00000531428 PIK3C2A-003 17077730-17207920 processed_transcript
  ENST00000532035 PIK3C2A-005 17169352-17207950 protein_coding
  ENST00000533645 PIK3C2A-002 17141322-17207947 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265970
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265970 5.904±0.00 7.083±0.00 6.072±0.00 4.875±0.00 5.051±0.00 5.327±0.00 9.600±0.00 3.049±0.00 7.780±0.00 0.995±0.00 5.127±0.05 3.587±0.00 7.693±0.18

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000836 CIL_000836_0001 VISTA 11:16591589-17196198
CIL_0003ZX CIL_0003ZX_0001 CGP 11:16778295-17077787
CIL_0003ZW CIL_0003ZW_0001 CGP 11:17074389-17207983
CIL_0003ZV CIL_0003ZV_0001 CGP 11:17077730-17349974

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005488 IEA binding
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0005942 IBA phosphatidylinositol 3-kinase complex
GO:0006644 TAS phospholipid metabolic process
GO:0006661 TAS phosphatidylinositol biosynthetic process
GO:0006887 TAS exocytosis
GO:0006897 IMP endocytosis
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008286 TAS insulin receptor signaling pathway
GO:0014829 TAS vascular smooth muscle contraction
GO:0016020 IDA membrane
GO:0016303 IBA 1-phosphatidylinositol-3-kinase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0031410 IEA cytoplasmic vesicle
GO:0031982 IDA vesicle
GO:0035004 TAS phosphatidylinositol 3-kinase activity
GO:0035005 TAS 1-phosphatidylinositol-4-phosphate 3-kinase activity
GO:0035091 IEA phosphatidylinositol binding
GO:0036092 IEA phosphatidylinositol-3-phosphate biosynthetic process
GO:0044281 TAS small molecule metabolic process
GO:0046854 IEA phosphatidylinositol phosphorylation
GO:0048008 TAS platelet-derived growth factor receptor signaling pathway
GO:0048015 IEA phosphatidylinositol-mediated signaling
GO:0048268 TAS clathrin coat assembly
GO:0070062 IDA extracellular vesicular exosome
GO:0071583 IEA negative regulation of zinc ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060841 pik3c2a phosphoinositide-3-kinase, class 2, alpha polypeptide protein_coding Danio_rerio
ENSMUSG00000030660 Pik3c2a phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide protein_coding Mus_musculus

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