C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: caspase 2, apoptosis-related cysteine protease
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000062052 casp2 7955 - 16:19610492-19640047 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000089230 casp2-001 19616966-19622522 protein_coding
  ENSDART00000122212 casp2-201 19610492-19639281 protein_coding
  ENSDART00000128388 casp2-002 19616864-19640047 protein_coding
  ENSDART00000137215 casp2-004 19612758-19617342 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverENSDART00000122212ENSDART00000128388ENSDART00000137215
Transcript ID Brain Heart Kidney Liver
ENSDART00000122212 1.495±0.92 2.361±0.64 1.875±0.80 0.128±0.00
ENSDART00000128388 1.533±0.00 1.160±0.06 3.361±0.00 N/A
ENSDART00000137215 N/A 1.555±0.00 N/A 0.589±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004197 IEA cysteine-type endopeptidase activity
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0006508 IEA proteolysis
GO:0006915 IEA apoptotic process
GO:0008233 IEA peptidase activity
GO:0008234 IEA cysteine-type peptidase activity
GO:0008630 IGI intrinsic apoptotic signaling pathway in response to DNA damage
GO:0016787 IEA hydrolase activity
GO:0042981 IEA regulation of apoptotic process
GO:0043065 IDA positive regulation of apoptotic process
GO:0043281 IGI regulation of cysteine-type endopeptidase activity involved in apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000106144 CASP2 caspase 2, apoptosis-related cysteine peptidase protein_coding Homo_sapiens
ENSMUSG00000029863 Casp2 caspase 2 protein_coding Mus_musculus

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