C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: caspase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029863 Casp2 10090 + 6:42264985-42282508 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031895 Casp2-001 42264985-42282508 protein_coding
  ENSMUST00000132246 Casp2-005 42267391-42268030 processed_transcript
  ENSMUST00000132398 Casp2-008 42276487-42280533 retained_intron
  ENSMUST00000139930 Casp2-004 42265056-42269122 retained_intron
  ENSMUST00000141669 Casp2-006 42268010-42269607 processed_transcript
  ENSMUST00000141727 Casp2-010 42279781-42280641 processed_transcript
  ENSMUST00000144821 Casp2-007 42269285-42279897 processed_transcript
  ENSMUST00000152893 Casp2-009 42279637-42280490 processed_transcript
  ENSMUST00000156829 Casp2-003 42265120-42280492 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031895ENSMUST00000132246ENSMUST00000156829
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031895 12.234±4.98 7.537±1.01 10.480±0.34 17.441±12.40 12.353±3.24 17.869±2.85 2.459±0.33 5.215±1.42 9.387±8.96 16.613±0.70 0.787±0.38 19.478±8.06 5.776±3.56 1.897±0.86
ENSMUST00000132246 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.614±0.00 N/A
ENSMUST00000156829 N/A N/A N/A 0.990±0.00 N/A N/A N/A N/A 0.412±0.00 N/A 0.582±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006VH CIL_0006VH_0002 CGP 6:42261970-42282508
CIL_0006VM CIL_0006VM_0002 CGP 6:42264985-42315756

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001554 IEA luteolysis
GO:0003407 IEA neural retina development
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0006508 RCA proteolysis
GO:0006977 IEA DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007420 IEA brain development
GO:0007568 IEA aging
GO:0008233 RCA peptidase activity
GO:0008630 IBA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0016020 IEA membrane
GO:0016485 IEA protein processing
GO:0019904 IEA protein domain specific binding
GO:0035234 IGI ectopic germ cell programmed cell death
GO:0043065 ISA positive regulation of apoptotic process
GO:0043066 ISA negative regulation of apoptotic process
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0071260 IEA cellular response to mechanical stimulus
GO:0097153 IDA cysteine-type endopeptidase activity involved in apoptotic process
GO:0097190 IDA apoptotic signaling pathway
GO:0097192 IMP extrinsic apoptotic signaling pathway in absence of ligand
GO:2001235 IGI positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062052 casp2 caspase 2, apoptosis-related cysteine protease protein_coding Danio_rerio
ENSG00000106144 CASP2 caspase 2, apoptosis-related cysteine peptidase protein_coding Homo_sapiens

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