C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: iduronate 2-sulfatase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000071699 ids 7955 - 14:21870885-21893036 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000106205 ids-001 21870885-21893012 protein_coding
  ENSDART00000132499 ids-002 21892151-21893036 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000106205ENSDART00000132499
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000106205 2.067±0.07 2.697±0.91 3.251±2.56 0.354±0.00 0.388±0.00
ENSDART00000132499 6.069±1.32 N/A 1.393±0.02 N/A 0.292±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000PK CIL_0000PK_0001 CGP 14:21343820-21893036

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004423 IDA iduronate-2-sulfatase activity
GO:0005737 IDA cytoplasm
GO:0008152 IEA metabolic process
GO:0008484 IEA sulfuric ester hydrolase activity
GO:0009790 IMP embryo development
GO:0030512 IMP negative regulation of transforming growth factor beta receptor signaling pathway
GO:0060536 IMP cartilage morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000010404 IDS iduronate 2-sulfatase protein_coding Homo_sapiens
ENSG00000241489 IDS Iduronate 2-sulfatase (Hunter syndrome), isoform CRA_e {ECO:0000313|EMBL:EAW61285.1}; Uncharacterized protein {ECO:0000313|Ensem protein_coding Homo_sapiens
ENSMUSG00000035847 Ids iduronate 2-sulfatase protein_coding Mus_musculus

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