C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: caspase 10, apoptosis-related cysteine peptidase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000003400 CASP10 9606 + 2:201182881-201229406 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000272879 CASP10-002 201183132-201229406 protein_coding
  ENST00000286186 CASP10-001 201182881-201221665 protein_coding
  ENST00000313728 CASP10-009 201183192-201217770 protein_coding
  ENST00000346817 CASP10-003 201183169-201220080 protein_coding
  ENST00000360132 CASP10-201 201182898-201221660 protein_coding
  ENST00000374650 CASP10-007 201183160-201200728 protein_coding
  ENST00000438843 CASP10-006 201183141-201208160 nonsense_mediated_decay
  ENST00000448480 CASP10-010 201183195-201229128 protein_coding
  ENST00000460140 CASP10-005 201183112-201206250 retained_intron
  ENST00000471191 CASP10-012 201187680-201196015 retained_intron
  ENST00000484926 CASP10-011 201183216-201186380 retained_intron
  ENST00000485408 CASP10-013 201187746-201193403 retained_intron
  ENST00000492363 CASP10-004 201185778-201217741 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000272879ENST00000286186ENST00000313728ENST00000346817ENST00000360132ENST00000374650ENST00000460140ENST00000471191
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000272879 N/A N/A 0.396±0.00 N/A N/A 2.122±0.00 0.476±0.00 N/A 1.115±0.00 1.351±0.00 N/A 3.451±0.00 N/A N/A
ENST00000286186 0.460±0.00 1.134±0.00 N/A 0.166±0.00 2.560±0.00 0.687±0.08 0.607±0.33 1.082±0.53 0.476±0.04 1.950±0.00 0.406±0.00 1.514±1.10 1.109±0.25 0.348±0.00
ENST00000313728 N/A N/A 0.606±0.00 N/A N/A N/A N/A 1.068±0.00 1.010±0.00 N/A N/A N/A N/A N/A
ENST00000346817 1.073±0.00 N/A 0.303±0.00 0.138±0.00 1.779±0.51 1.485±0.51 0.692±0.03 0.724±0.33 0.644±0.14 2.976±1.84 0.083±0.00 1.594±0.54 1.393±0.46 0.536±0.00
ENST00000360132 N/A 1.246±0.00 N/A N/A N/A N/A N/A N/A 0.203±0.00 N/A 0.219±0.00 N/A 0.262±0.00 0.963±0.00
ENST00000374650 N/A N/A 0.603±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000460140 N/A N/A N/A N/A 4.198±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000471191 N/A N/A N/A N/A N/A 7.552±0.00 N/A 3.068±0.00 5.268±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089O CIL_00089O_0001 VISTA 2:201132231-201734391

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004197 TAS:IEA cysteine-type endopeptidase activity
GO:0005515 IPI:IEA protein binding
GO:0005737 IBA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006508 IEA proteolysis
GO:0006915 IBA:IEA apoptotic process
GO:0008234 IEA cysteine-type peptidase activity
GO:0031265 IDA CD95 death-inducing signaling complex
GO:0031625 IPI ubiquitin protein ligase binding
GO:0035877 IPI death effector domain binding
GO:0042981 IEA regulation of apoptotic process
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087 TAS innate immune response
GO:0097190 TAS apoptotic signaling pathway
GO:0097199 IMP cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO:0097342 IDA ripoptosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070272 casp8l2 caspase 8, apoptosis-related cysteine peptidase, like 2 protein_coding Danio_rerio

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