C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: caspase 8, apoptosis-related cysteine peptidase, like 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000070272 casp8l2 7955 + 9:1328208-1346468 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000014766 casp8l2-201 1334168-1346468 protein_coding
  ENSDART00000082478 casp8l2-001 1328208-1335517 protein_coding
  ENSDART00000146016 casp8l2-002 1341262-1346468 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000014766ENSDART00000082478ENSDART00000146016
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000014766 N/A 0.254±0.00 0.253±0.00 N/A N/A
ENSDART00000082478 0.085±0.00 0.921±0.39 N/A 0.155±0.00 0.243±0.00
ENSDART00000146016 0.170±0.09 0.767±0.44 N/A 0.290±0.00 0.431±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004197 IEA cysteine-type endopeptidase activity
GO:0005515 IEA protein binding
GO:0006508 IEA proteolysis
GO:0006915 IEA apoptotic process
GO:0008233 IEA peptidase activity
GO:0008234 IEA cysteine-type peptidase activity
GO:0016787 IEA hydrolase activity
GO:0042981 IEA regulation of apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000003400 CASP10 caspase 10, apoptosis-related cysteine peptidase protein_coding Homo_sapiens
ENSG00000064012 CASP8 caspase 8, apoptosis-related cysteine peptidase protein_coding Homo_sapiens
ENSMUSG00000026029 Casp8 caspase 8 protein_coding Mus_musculus

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