C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: paraoxonase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000005421 PON1 9606 - 7:95297676-95324707 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000222381 PON1-001 95297676-95324707 protein_coding
  ENST00000433729 PON1-003 95298914-95324476 nonsense_mediated_decay
  ENST00000462594 PON1-004 95298749-95302403 retained_intron
  ENST00000470502 PON1-006 95311490-95318587 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000222381ENST00000433729ENST00000462594ENST00000470502
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000222381 0.004±0.00 0.047±0.00 0.140±0.00 0.187±0.00 0.039±0.01 0.056±0.03 22.628±0.00 6.423±6.38 N/A 0.016±0.00 0.073±0.06 N/A 0.186±0.00
ENST00000433729 N/A N/A N/A 0.164±0.05 0.049±0.00 0.022±0.00 27.934±27.76 73.805±0.00 N/A N/A 0.194±0.12 0.026±0.00 N/A
ENST00000462594 N/A N/A 0.166±0.00 N/A N/A N/A N/A 56.344±0.00 N/A N/A 0.393±0.06 0.099±0.00 0.423±0.08
ENST00000470502 N/A N/A N/A N/A N/A N/A 0.231±0.00 N/A 0.296±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00053I CIL_00053I_0001 CGP 7:94907202-95324707
CIL_0003BB CIL_0003BB_0004 CGP 7:95297676-95396368

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004063 IDA aryldialkylphosphatase activity
GO:0004064 IDA:IEA arylesterase activity
GO:0005509 IDA calcium ion binding
GO:0005543 IDA phospholipid binding
GO:0005576 NAS extracellular region
GO:0005615 IDA extracellular space
GO:0006629 IEA lipid metabolic process
GO:0009058 IEA biosynthetic process
GO:0009605 NAS response to external stimulus
GO:0009636 IEA response to toxic substance
GO:0010875 IDA positive regulation of cholesterol efflux
GO:0016311 IEA dephosphorylation
GO:0016844 IEA strictosidine synthase activity
GO:0019439 IDA aromatic compound catabolic process
GO:0031667 IEA response to nutrient levels
GO:0032411 IDA positive regulation of transporter activity
GO:0034364 TAS high-density lipoprotein particle
GO:0034366 IDA spherical high-density lipoprotein particle
GO:0042803 IDA protein homodimerization activity
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0046395 IDA carboxylic acid catabolic process
GO:0046434 IDA organophosphate catabolic process
GO:0046470 IDA phosphatidylcholine metabolic process
GO:0051099 IDA positive regulation of binding
GO:0070062 IDA extracellular vesicular exosome
GO:0070542 IEA response to fatty acid
GO:0072562 IDA blood microparticle
GO:1902617 IEA response to fluoride

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016856 pon2 paraoxonase 2 protein_coding Danio_rerio
ENSDARG00000032496 pon1 paraoxonase 1 protein_coding Danio_rerio
ENSDARG00000040290 zgc:174637 zgc:174637 protein_coding Danio_rerio
ENSDARG00000097789 zgc:174637 zgc:174637 protein_coding Danio_rerio
ENSMUSG00000002588 Pon1 paraoxonase 1 protein_coding Mus_musculus

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