C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: paraoxonase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000002588 Pon1 10090 - 6:5168090-5193946 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000002663 Pon1-001 5168090-5193946 protein_coding
  ENSMUST00000176933 Pon1-002 5185549-5193763 retained_intron
  ENSMUST00000176945 Pon1-004 5171783-5193784 protein_coding
  ENSMUST00000177159 Pon1-003 5168495-5193784 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000002663ENSMUST00000176945ENSMUST00000177159
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000002663 2.415±0.76 1.258±0.80 0.384±0.12 0.055±0.02 3.749±0.46 0.189±0.09 1.204±0.85 0.503±0.18 235.480±204.53 26.725±5.74 0.562±0.20 1.065±1.72 0.123±0.15 0.028±0.00
ENSMUST00000176945 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.289±0.00 0.057±0.00 N/A
ENSMUST00000177159 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.260±0.00 0.035±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00053I CIL_00053I_0002 CGP 6:4902917-5193946
CIL_0003BB CIL_0003BB_0006 CGP 6:5168090-5256286

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004063 ISS aryldialkylphosphatase activity
GO:0004064 ISS arylesterase activity
GO:0005509 ISS calcium ion binding
GO:0005543 IEA phospholipid binding
GO:0005576 IEA extracellular region
GO:0005615 IEA extracellular space
GO:0006629 IEA lipid metabolic process
GO:0008015 TAS blood circulation
GO:0008035 TAS high-density lipoprotein particle binding
GO:0008203 TAS cholesterol metabolic process
GO:0009636 IMP response to toxic substance
GO:0010875 IEA positive regulation of cholesterol efflux
GO:0016311 IEA dephosphorylation
GO:0019439 IEA aromatic compound catabolic process
GO:0031667 IEA response to nutrient levels
GO:0032411 IEA positive regulation of transporter activity
GO:0034366 IEA spherical high-density lipoprotein particle
GO:0042803 IEA protein homodimerization activity
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0046395 IEA carboxylic acid catabolic process
GO:0046434 IEA organophosphate catabolic process
GO:0046470 IEA phosphatidylcholine metabolic process
GO:0051099 IEA positive regulation of binding
GO:0070062 IEA extracellular vesicular exosome
GO:0070542 IEA response to fatty acid
GO:0072562 IEA blood microparticle
GO:1902617 IEA response to fluoride

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016856 pon2 paraoxonase 2 protein_coding Danio_rerio
ENSDARG00000032496 pon1 paraoxonase 1 protein_coding Danio_rerio
ENSDARG00000040290 zgc:174637 zgc:174637 protein_coding Danio_rerio
ENSDARG00000097789 zgc:174637 zgc:174637 protein_coding Danio_rerio
ENSG00000005421 PON1 paraoxonase 1 protein_coding Homo_sapiens

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