C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: scinderin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000006747 SCIN 9606 + 7:12570577-12653603 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000297029 SCIN-001 12570686-12653603 protein_coding
  ENST00000341757 SCIN-002 12570577-12653104 nonsense_mediated_decay
  ENST00000417018 SCIN-007 12570719-12581105 protein_coding
  ENST00000436854 SCIN-006 12570721-12578150 nonsense_mediated_decay
  ENST00000473722 SCIN-004 12611031-12629111 processed_transcript
  ENST00000476649 SCIN-003 12622838-12626541 retained_intron
  ENST00000486980 SCIN-005 12595549-12625071 processed_transcript
  ENST00000518849 SCIN-009 12589429-12622884 protein_coding
  ENST00000519209 SCIN-008 12589433-12653602 protein_coding
  ENST00000523729 SCIN-010 12588928-12625052 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000297029ENST00000341757ENST00000436854ENST00000473722ENST00000476649ENST00000518849ENST00000519209
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000297029 0.073±0.00 N/A 4.378±0.00 0.787±0.42 4.026±3.08 2.858±2.65 0.049±0.00 19.148±0.00 N/A 1.359±0.42 2.364±1.26 7.784±1.64 N/A
ENST00000341757 N/A N/A 2.765±0.00 0.488±0.30 4.877±0.00 N/A N/A 4.496±4.46 0.930±0.00 N/A 3.525±0.37 6.690±0.00 1.081±0.41
ENST00000436854 N/A 0.240±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000473722 N/A N/A N/A N/A 1.067±0.00 N/A N/A N/A 1.320±0.00 1.794±0.00 4.255±0.00 N/A N/A
ENST00000476649 N/A N/A 5.986±0.00 N/A N/A 3.810±0.00 0.077±0.00 N/A N/A 3.524±0.00 N/A N/A N/A
ENST00000518849 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.940±0.00 N/A N/A
ENST00000519209 N/A 0.069±0.00 N/A N/A N/A N/A 0.073±0.00 N/A N/A N/A N/A N/A 0.597±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001786 ISS phosphatidylserine binding
GO:0003779 ISS:IEA actin binding
GO:0005509 ISS calcium ion binding
GO:0005545 TAS 1-phosphatidylinositol binding
GO:0005546 ISS phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 ISS cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005938 ISS cell cortex
GO:0008285 IMP negative regulation of cell proliferation
GO:0017156 ISS calcium ion-dependent exocytosis
GO:0032330 ISS regulation of chondrocyte differentiation
GO:0043065 IMP positive regulation of apoptotic process
GO:0043234 IEA protein complex
GO:0045010 ISS actin nucleation
GO:0045654 IMP positive regulation of megakaryocyte differentiation
GO:0051014 IMP actin filament severing
GO:0051015 ISS actin filament binding
GO:0051047 ISS positive regulation of secretion
GO:0051693 IEA actin filament capping
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010728 scin scinderin protein_coding Danio_rerio
ENSMUSG00000002565 Scin scinderin protein_coding Mus_musculus

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