C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proteasome (prosome, macropain) subunit, beta type, 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000008018 PSMB1 9606 - 6:170535117-170553341 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262193 PSMB1-001 170535117-170553341 protein_coding
  ENST00000462957 PSMB1-002 170535222-170550441 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262193ENST00000462957
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262193 113.902±0.00 129.164±0.00 17.508±0.00 60.830±15.84 67.433±49.66 38.538±5.93 39.406±25.94 75.716±35.49 66.090±39.26 58.744±39.25 63.808±18.36 179.620±103.66 148.588±11.78 63.215±1.01
ENST00000462957 N/A N/A 1.583±0.00 N/A 2.433±0.00 N/A N/A N/A N/A 3.971±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008DG CIL_0008DG_0001 VISTA 6:170138007-170739776
CIL_00018D CIL_00018D_0001 CGP 6:170295321-170553341
CIL_00018G CIL_00018G_0001 CGP 6:170535117-170572870

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA proteasome complex
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0004298 IEA threonine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0005839 ISS:IEA proteasome core complex
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051603 IEA proteolysis involved in cellular protein catabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009640 psmb1 proteasome (prosome, macropain) subunit, beta type, 1 protein_coding Danio_rerio
ENSMUSG00000014769 Psmb1 proteasome (prosome, macropain) subunit, beta type 1 protein_coding Mus_musculus

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