C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: iodotyrosine deiodinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000009765 IYD 9606 + 6:150368892-150405969 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000229447 IYD-002 150368892-150404628 protein_coding
  ENST00000344419 IYD-001 150368892-150405969 protein_coding
  ENST00000367335 IYD-003 150368953-150398109 nonsense_mediated_decay
  ENST00000392255 IYD-006 150368997-150396816 protein_coding
  ENST00000392256 IYD-004 150368953-150398109 protein_coding
  ENST00000422583 IYD-007 150369155-150398109 nonsense_mediated_decay
  ENST00000425615 IYD-008 150369977-150395532 protein_coding
  ENST00000500320 IYD-005 150368997-150396890 protein_coding
  ENST00000546121 IYD-009 150369089-150389630 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000229447ENST00000344419ENST00000392255ENST00000392256ENST00000422583ENST00000500320
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000229447 0.021±0.00 N/A 3.258±0.00 0.011±0.01 0.243±0.23 0.379±0.25 N/A 3.227±2.66 0.268±0.22 0.173±0.00 0.005±0.00 0.777±0.60 0.007±0.00 0.028±0.00
ENST00000344419 N/A 0.019±0.00 0.460±0.00 0.016±0.00 N/A N/A 0.010±0.00 0.107±0.00 N/A N/A 0.002±0.00 0.382±0.00 N/A 0.015±0.00
ENST00000392255 N/A 0.068±0.00 N/A N/A 0.028±0.00 N/A 0.016±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000392256 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.266±0.00 N/A N/A
ENST00000422583 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.077±0.00 N/A
ENST00000500320 0.034±0.00 0.020±0.00 N/A 0.014±0.00 0.018±0.00 N/A 0.005±0.00 N/A N/A N/A N/A N/A 0.011±0.00 0.027±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005OL CIL_0005OL_0001 CGP 6:150143076-150405969
CIL_0005OK CIL_0005OK_0001 CGP 6:150368892-150843665

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004447 IEA iodide peroxidase activity
GO:0005886 TAS plasma membrane
GO:0006590 TAS thyroid hormone generation
GO:0016021 IEA integral component of membrane
GO:0016491 TAS:IEA oxidoreductase activity
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076056 IYD (1 of 2) iodotyrosine deiodinase protein_coding Danio_rerio
ENSDARG00000094444 iyd iodotyrosine deiodinase protein_coding Danio_rerio
ENSMUSG00000019762 Iyd iodotyrosine deiodinase protein_coding Mus_musculus

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