C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lactotransferrin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000012223 LTF 9606 - 3:46435645-46485234 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000231751 LTF-001 46435645-46465163 protein_coding
  ENST00000417439 LTF-003 46436193-46464868 protein_coding
  ENST00000426532 LTF-011 46436019-46463671 protein_coding
  ENST00000431944 LTF-005 46455429-46464905 protein_coding
  ENST00000443496 LTF-002 46436201-46485234 protein_coding
  ENST00000462667 LTF-009 46454014-46455823 retained_intron
  ENST00000478874 LTF-007 46438095-46463644 processed_transcript
  ENST00000493056 LTF-008 46438034-46441905 processed_transcript
  ENST00000498301 LTF-004 46459657-46485223 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000231751ENST00000417439ENST00000426532ENST00000478874ENST00000493056ENST00000498301
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000231751 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.019±0.00 0.256±0.00 N/A N/A
ENST00000417439 8.162±0.00 4.183±0.00 N/A 0.593±0.00 21.790±19.70 0.313±0.00 N/A 14.735±0.00 1.072±0.61 29.723±19.15 0.244±0.00 0.243±0.16 N/A 11.927±11.81
ENST00000426532 3.954±0.00 6.156±0.00 1.621±0.00 0.107±0.00 35.998±27.84 0.585±0.20 0.869±0.67 9.361±0.00 1.973±1.70 74.078±55.65 N/A 0.724±0.39 1.516±0.97 31.798±0.00
ENST00000478874 N/A N/A N/A 0.568±0.00 N/A 0.849±0.00 N/A N/A N/A N/A N/A 1.473±0.00 N/A 0.572±0.00
ENST00000493056 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.177±0.00 N/A
ENST00000498301 N/A N/A N/A N/A N/A 0.530±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001503 IEA ossification
GO:0001817 IDA regulation of cytokine production
GO:0001895 IEP retina homeostasis
GO:0002227 IDA innate immune response in mucosa
GO:0003677 IEA DNA binding
GO:0004252 TAS serine-type endopeptidase activity
GO:0005506 IDA iron ion binding
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006508 IEA proteolysis
GO:0006826 IEA iron ion transport
GO:0006879 IEA cellular iron ion homeostasis
GO:0006959 TAS humoral immune response
GO:0008199 IEA ferric iron binding
GO:0008201 IDA heparin binding
GO:0008233 IEA peptidase activity
GO:0019731 IDA antibacterial humoral response
GO:0019732 IDA antifungal humoral response
GO:0030141 IDA secretory granule
GO:0031665 IDA negative regulation of lipopolysaccharide-mediated signaling pathway
GO:0032680 IDA regulation of tumor necrosis factor production
GO:0033214 TAS iron assimilation by chelation and transport
GO:0033690 IDA positive regulation of osteoblast proliferation
GO:0034145 IMP positive regulation of toll-like receptor 4 signaling pathway
GO:0042581 IDA specific granule
GO:0043066 ISS negative regulation of apoptotic process
GO:0043123 IDA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043539 IDA protein serine/threonine kinase activator activity
GO:0045669 IDA positive regulation of osteoblast differentiation
GO:0051092 IDA positive regulation of NF-kappaB transcription factor activity
GO:0051701 TAS interaction with host
GO:0052572 TAS response to host immune response
GO:0060349 IDA bone morphogenesis
GO:0070062 IDA extracellular vesicular exosome
GO:0071902 IDA positive regulation of protein serine/threonine kinase activity
GO:0090382 TAS phagosome maturation
GO:0097013 TAS phagocytic vesicle lumen
GO:1900159 ISS positive regulation of bone mineralization involved in bone maturation
GO:1900229 IDA negative regulation of single-species biofilm formation in or on host organism
GO:1902732 IDA positive regulation of chondrocyte proliferation
GO:2000308 ISS negative regulation of tumor necrosis factor (ligand) superfamily member 11 production
GO:2001205 ISS negative regulation of osteoclast development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016771 tfa transferrin-a protein_coding Danio_rerio
ENSMUSG00000032496 Ltf lactotransferrin protein_coding Mus_musculus

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