C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pleckstrin homology domain containing, family B (evectins) member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000021300 PLEKHB1 9606 + 11:73646178-73662819 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000227214 PLEKHB1-003 73647549-73662819 protein_coding
  ENST00000354190 PLEKHB1-001 73646178-73662819 protein_coding
  ENST00000398492 PLEKHB1-002 73646178-73662819 protein_coding
  ENST00000398494 PLEKHB1-004 73647609-73662819 protein_coding
  ENST00000426191 PLEKHB1-008 73652440-73662812 retained_intron
  ENST00000535129 PLEKHB1-007 73648690-73661720 protein_coding
  ENST00000535582 PLEKHB1-013 73647655-73660770 protein_coding
  ENST00000536527 PLEKHB1-009 73646579-73651437 protein_coding
  ENST00000538227 PLEKHB1-016 73647655-73660873 protein_coding
  ENST00000539157 PLEKHB1-015 73647655-73660756 protein_coding
  ENST00000540157 PLEKHB1-021 73652620-73660925 retained_intron
  ENST00000540431 PLEKHB1-023 73649012-73661551 protein_coding
  ENST00000541597 PLEKHB1-019 73647932-73661522 protein_coding
  ENST00000541760 PLEKHB1-017 73647689-73652070 retained_intron
  ENST00000542389 PLEKHB1-020 73648914-73660795 protein_coding
  ENST00000543085 PLEKHB1-010 73647626-73661665 protein_coding
  ENST00000543524 PLEKHB1-018 73647714-73661496 protein_coding
  ENST00000544282 PLEKHB1-024 73662353-73662815 processed_transcript
  ENST00000544532 PLEKHB1-011 73647653-73651879 processed_transcript
  ENST00000545106 PLEKHB1-022 73660309-73661734 retained_intron
  ENST00000545798 PLEKHB1-012 73647655-73651851 protein_coding
  ENST00000546251 PLEKHB1-014 73647655-73660766 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000227214ENST00000398494ENST00000426191ENST00000535129ENST00000535582ENST00000536527ENST00000538227ENST00000539157ENST00000540157ENST00000540431ENST00000541760ENST00000544282
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000227214 2.347±0.00 6.267±0.00 166.863±102.31 3.984±0.00 34.586±0.00 2.990±0.00 2.740±0.00 0.593±0.00 6.576±5.38 2.748±0.00 13.633±12.59 1.412±0.12 7.504±1.24
ENST00000398494 N/A N/A N/A N/A 0.519±0.00 N/A 0.064±0.00 0.446±0.00 N/A 0.351±0.00 N/A N/A N/A
ENST00000426191 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.520±0.00
ENST00000535129 N/A N/A N/A N/A N/A 0.115±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000535582 N/A N/A N/A N/A 0.612±0.00 N/A N/A N/A N/A N/A 2.700±0.00 N/A N/A
ENST00000536527 N/A N/A N/A N/A N/A N/A N/A 0.375±0.00 N/A N/A N/A N/A N/A
ENST00000538227 N/A N/A N/A N/A N/A N/A N/A N/A 0.464±0.00 0.631±0.00 N/A N/A N/A
ENST00000539157 N/A N/A N/A N/A 0.412±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000540157 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.117±0.00
ENST00000540431 N/A N/A N/A N/A 0.907±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000541760 N/A N/A N/A 1.959±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000544282 N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.651±0.00 N/A 1.197±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003JC CIL_0003JC_0002 CGP 11:73646178-73761137

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004871 TAS signal transducer activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0007275 IEA multicellular organismal development
GO:0007602 NAS phototransduction
GO:0008022 IEA protein C-terminus binding
GO:0016021 IDA integral component of membrane
GO:0042803 IEA protein homodimerization activity
GO:0045595 IEA regulation of cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063519 PLEKHB1 (1 of 2) pleckstrin homology domain containing, family B (evectins) member 1 protein_coding Danio_rerio
ENSDARG00000088943 PLEKHB1 (2 of 2) pleckstrin homology domain containing, family B (evectins) member 1 protein_coding Danio_rerio
ENSMUSG00000030701 Plekhb1 pleckstrin homology domain containing, family B (evectins) member 1 protein_coding Mus_musculus

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