C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: GRB2-associated binding protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000033327 GAB2 9606 - 11:78215297-78418348 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000340149 GAB2-002 78215297-78341880 protein_coding
  ENST00000361507 GAB2-001 78215297-78417806 protein_coding
  ENST00000526030 GAB2-004 78226957-78417822 processed_transcript
  ENST00000528329 GAB2-007 78226620-78231932 processed_transcript
  ENST00000528886 GAB2-003 78250271-78418348 protein_coding
  ENST00000530915 GAB2-005 78250357-78417779 protein_coding
  ENST00000534823 GAB2-006 78280460-78417771 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000340149ENST00000361507ENST00000534823
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000340149 N/A N/A N/A 1.087±0.00 N/A N/A N/A 0.362±0.00 N/A N/A N/A N/A N/A N/A
ENST00000361507 20.346±0.00 2.781±0.00 0.492±0.00 11.492±8.96 6.135±5.29 5.199±4.44 2.079±1.86 1.294±0.92 4.421±0.00 9.656±8.07 2.763±0.00 8.054±4.31 5.584±1.81 5.772±1.27
ENST00000534823 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.678±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005068 IDA transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005515 IPI protein binding
GO:0005547 ISS phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0007169 IDA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008284 IDA positive regulation of cell proliferation
GO:0016477 IEA cell migration
GO:0030316 IMP osteoclast differentiation
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0043306 ISS positive regulation of mast cell degranulation
GO:0043325 ISS phosphatidylinositol-3,4-bisphosphate binding
GO:0045087 TAS innate immune response
GO:0048015 ISS phosphatidylinositol-mediated signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074577 gab2 GRB2-associated binding protein 2 protein_coding Danio_rerio
ENSMUSG00000004508 Gab2 growth factor receptor bound protein 2-associated protein 2 protein_coding Mus_musculus

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